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Updated: Aug 19, 2026

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
Published on: October 2, 2012
Fluorometric variable-temperature kinetics investigations of the transesterification reaction of procaine with
Ali Reza Harifi-Mood1, Saeed Haghighi, Mohammad Reza Gholami
1Department of Chemistry, Sharif University of Technology, Tehran, Iran.
Purpose:
Variable-Temperature Kinetics has been used to obtain the rate constants of the reaction at various temperatures during one kinetic run.
Methods:
Pseudo-first-order rate constants for the transesterification of procaine with aliphatic alcohols ethanol, n-propanol and tert-butanol were obtained by the fluorescence spectroscopy using the variable-temperature kinetics (VTK) method.
Results:
The activation parameters of the reactions were calculated (24-28 kcal x mol(-1)). The half-life of the procaine decreases in the ethanol solution compared with the other alcoholic solutions in the presence of sodium ethoxide.
Conclusions:
The investigation time of the reactions is reduced to one-tenth of the one used for usual kinetic methods.
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