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Related Experiment Videos

Does hypnotizability modulate the stress-related endothelial dysfunction?

Zoltán Jambrik1, Enrica L Santarcangelo, Brunello Ghelarducci

  • 1Echocardiography Lab, Institute of Clinical Physiology, CNR, Pisa, Italy.

Brain Research Bulletin
|May 18, 2004
PubMed
Summary
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Hypnotizability may protect against vascular disease. Highly hypnotizable individuals showed no stress-induced endothelial dysfunction, unlike those with low hypnotizability, suggesting a protective role for hypnotizability.

Area of Science:

  • Cardiovascular Physiology
  • Neuroscience
  • Psychology

Background:

  • Previous research indicates hypnotizability protects against cardiac stress effects.
  • Hypnosis has been shown to prevent vascular changes in highly hypnotizable individuals.

Purpose of the Study:

  • To determine if high hypnotizability protects against vascular stress in awake individuals.
  • To investigate vascular responses to cognitive stress in subjects with high and low hypnotic susceptibility.

Main Methods:

  • Non-invasive ultrasound methodology was used to evaluate brachial artery flow-mediated dilation (FMD).
  • FMD was measured in highly (Highs) and lowly (Lows) hypnotizable subjects during cognitive stress (mental computation).

Main Results:

Related Experiment Videos

  • Highly hypnotizable individuals (Highs) did not show stress-induced endothelial dysfunction (FMD decrement).
  • Lowly hypnotizable individuals (Lows) exhibited stress-related endothelial dysfunction.
  • Results in awake Highs mirrored findings in previously studied hypnotized Highs.

Conclusions:

  • Hypnotizability appears to be a protective factor against vascular disease.
  • Individual differences in hypnotic susceptibility influence vascular response to stress.
  • Further research into hypnotizability as a protective factor in vascular health is warranted.