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Persistent severe amnesia due to seizure recurrence after unilateral temporal lobectomy
Thomas Dietl1, Horst Urbach, Christoph Helmstaedter
1Department of Epileptology, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany. t.dietl@web.de
Epilepsy & Behavior : E&B
|May 18, 2004
Abstract:
Anterograde amnesia is a severely disabling state which has been reported as a consequence of bilateral mesiotemporal lesions in humans. In the present paper, recurrent epileptic seizures after temporal lobectomy are described as a rare cause of severe amnesia in two patients. Diffusion-weighted MRI in one patient showed cytotoxic edema during a nonconvulsive status epilepticus and subsequent progressive hippocampal atrophy within the following month. In the other patient, repeated conventional MRI revealed no structural abnormalities in the contralateral temporal lobe.