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Updated: Aug 24, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
Extramedullary hematopoiesis occurring as a nasal polyp in a man with a myeloproliferative disorder
Lawrence V Brennan1, Thomas Mayer, James Devitt
1Department of Hematology/Oncology, St. Luke Hospital, Fort Thomas, KY 41075, USA. LBrennan@ohcmail.com
Abstract:
We describe the case of a patient with a known myeloproliferative disorder who presented with epistaxis and what clinically appeared to be a nasal polyp. The mass was resected and proved to represent a focus of extramedullary hematopoiesis. The patient subsequently developed extramedullary hematopoiesis of the skin and the stomach wall. Following nasal polypectomy, he did well for a time, but he eventually died as a result of other complications of his disease. This unique case serves as a reminder that common rhinologic complaints can be a sign of significant and life-threatening pathology.
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