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Related Experiment Videos

Diastolic function in Chagas' disease: an echo and tissue Doppler imaging study.

M V L Barros1, F S Machado, A L P Ribeiro

  • 1Ecoar-Noninvasive Diagnostic Medicine, Brazil. ecoar@gold.com.br

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
|May 19, 2004
PubMed
Summary

Tissue Doppler imaging (TDI) effectively detects diastolic dysfunction in Chagas

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Infectious Diseases

Background:

  • Chagas' disease (Chd) can affect cardiac function, specifically left ventricular filling.
  • Understanding diastolic dysfunction patterns is crucial for managing Chagas' cardiomyopathy.

Purpose of the Study:

  • To investigate left ventricular filling patterns in patients with Chagas' disease.
  • To evaluate the utility of echocardiography, Doppler, and tissue Doppler imaging (TDI) in assessing diastolic function in Chagas' disease.

Main Methods:

  • 169 Chagas' disease patients underwent echocardiography, Doppler, and TDI.
  • Patients were categorized into four left ventricular filling groups.
  • TDI of basal left ventricular walls was performed.

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Main Results:

  • Diastolic dysfunction was identified in 21.3% of patients, correlating with reduced ejection fraction (r = 0.78).
  • TDI septal e' wave measurement demonstrated high sensitivity (97%) and specificity (84%) for detecting diastolic dysfunction.
  • The septal E/e' ratio proved highly sensitive (100%) and specific (88%) for advanced diastolic dysfunction.

Conclusions:

  • Echocardiography and Doppler, particularly TDI, are valuable tools for characterizing left ventricular diastolic function in Chagas' disease.
  • TDI is useful for diagnosing diastolic dysfunction in patients with Chagas' disease.