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Optic nerve head morphometry in healthy adults using confocal laser scanning tomography
M M Hermann1, I Theofylaktopoulos, N Bangard
1Department of Ophthalmology, University of Cologne, Germany. manuelhermann@gmx.de
The British Journal of Ophthalmology
|May 19, 2004
Summary
This study established new Heidelberg Retina Tomograph (HRT) normative data for optic nerve head (ONH) characteristics in healthy adults. The findings provide a valuable database for comparing healthy and glaucomatous eyes.
Area of Science:
- Ophthalmology
- Medical Imaging
- Optometry
Background:
- Confocal laser scanning tomography is crucial for assessing optic nerve head (ONH) structure.
- Establishing normative databases is essential for diagnosing ocular pathologies like glaucoma.
Purpose of the Study:
- To establish a new normative database of optic nerve head (ONH) characteristics using the Heidelberg Retina Tomograph (HRT I).
- To facilitate the comparison of ONH parameters between healthy and glaucomatous eyes.
Main Methods:
- A cross-sectional study involving 882 healthy white adults (1764 eyes).
- Optic nerve head (ONH) tomography performed using Heidelberg Retina Tomograph (HRT I).
- Standard ophthalmological examinations including visual acuity, slit lamp examination, tonometry, and perimetry were conducted.
Main Results:
- Mean disc area was 1.82 mm², mean cup area was 0.44 mm², and mean cup:disc area ratio was 0.22.
- Right eyes exhibited significantly thicker mean retinal nerve fibre layer thickness (RNFLT) than left eyes (p<0.001).
- Age and sex did not show statistically significant differences in ONH parameters.
Conclusions:
- The study provides a new normative HRT database for optic nerve head (ONH) parameters in a healthy adult population.
- Observed differences in ONH measurements between right and left eyes, and age/sex variations, are not clinically significant.
- This database serves as a benchmark for differentiating healthy eyes from those affected by glaucoma.