Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Contractures in neuromuscular disease.

E R Johnson1, W M Fowler, J S Lieberman

  • 1Department of Physical Medicine and Rehabilitation, University of California--Davis, Sacramento 95817.

Archives of Physical Medicine and Rehabilitation
|September 11, 1992
PubMed
Summary

Contractures are common in neuromuscular diseases, especially Duchenne muscular dystrophy. They are more frequent in lower limbs, myopathic conditions, X-linked diseases, and rapidly progressing conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting spectroscopic accuracy for dispersion bound systems from ab initio techniques: Translational eigenstates of Ne@C70.

The Journal of chemical physics·2024
Same author

Small molecule binding to surface-supported single-site transition-metal reaction centres.

Nature communications·2022
Same author

Chlorosis-An Obituary.

Annals of medical history·2021
Same author

Wave packets in the anomalous Ostrovsky equation.

Physical review. E·2019
Same author

Structure and formation of highly luminescent protein-stabilized gold clusters.

Chemical science·2018
Same author

Whitham modulation theory for the Ostrovsky equation.

Proceedings. Mathematical, physical, and engineering sciences·2017

Area of Science:

  • Neurology
  • Orthopedics
  • Genetics

Background:

  • Contractures are a common complication in patients with neuromuscular diseases.
  • Understanding the prevalence and risk factors for contractures is crucial for patient management.

Purpose of the Study:

  • To analyze the incidence and characteristics of contractures in a cohort of patients with neuromuscular diseases.
  • To identify specific neuromuscular disease types and progression factors associated with a higher likelihood of contractures.

Main Methods:

  • Retrospective analysis of 230 patients diagnosed with 11 different neuromuscular diseases over a five-year period.
  • Data collected included contracture presence, severity (mean maximal loss of range), and relative contracture indices.
  • Statistical analysis was performed to compare contracture occurrence across different disease categories and patient groups.

Related Experiment Videos

Main Results:

  • Duchenne muscular dystrophy exhibited the highest percentage of contractures among the studied diseases.
  • Contractures were significantly more prevalent in lower extremities compared to upper extremities (p < .001).
  • Myopathic, X-linked, and rapidly progressive diseases showed a significantly higher incidence of contractures than their counterparts (neuropathic, non-X-linked, slowly progressive).

Conclusions:

  • Contracture development in neuromuscular diseases is influenced by disease type, genetic linkage, and progression rate.
  • Lower extremity involvement is a key factor in contracture prevalence.
  • These findings highlight the need for targeted interventions and monitoring for contractures in at-risk neuromuscular disease populations.