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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
Published on: August 16, 2018
Identification and optimization of novel partial agonists of neuromedin B receptor using parallel synthesis
Stephen J Shuttleworth1, Mike E Lizarzaburu, Anne Chai
1Department of Chemistry, Tularik Inc., 1120 Veterans Boulevard, South San Francisco, CA 94080, USA.
Bioorganic & Medicinal Chemistry Letters
|May 20, 2004
Abstract:
The design and parallel synthesis of potent, small molecule partial agonists of Neuromedin B receptor based on the 3-amino-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid amide core is described.
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