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Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
First total synthesis of structurally unique flavonoids and their strong anti-inflammatory effect
Takashi Nakatsuka1, Yoshiaki Tomimori, Yoshiaki Fukuda
1Daiichi Suntory Biomedical Research Co, Ltd, 1-1-1, Wakayamadai, Shimamoto-cho, Mishima-gun, Osaka 618-8513, Japan. takashi_nakatsuka@dsup.co.jp
Bioorganic & Medicinal Chemistry Letters
|May 20, 2004
Abstract:
The first total synthesis of structurally unique flavonoids 1a and 1b is described. These compounds showed very strong anti-inflammatory effect against delayed hypersensitivity in a mouse model.
