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Assessing the impact of wastage on pediatric vaccine immunization formulary costs using a vaccine selection algorithm

Sheldon H Jacobson1, Tamana Karnani, Edward C Sewell

  • 1Department of Mechanical and Industrial Engineering, University of Illinois, 1206 West Green Street (MC-244), Urbana, IL 61801, USA. shj@uiuc.edu

Vaccine
|May 20, 2004
PubMed

Insights

Vaccine wastage significantly impacts pediatric immunization costs. This study introduces an algorithm to optimize vaccine selection by accounting for wastage, aiding healthcare providers in cost-effective decisions.

Area of Science:

  • Health economics
  • Pharmaceutical sciences
  • Public health

Background:

  • Pediatric immunization is crucial for disease prevention.
  • An increasing number of vaccines creates a complex immunization schedule.
  • Operations research models aid vaccine procurement but often exclude wastage costs.

Purpose of the Study:

  • To develop and evaluate a vaccine selection algorithm incorporating vaccine wastage data.
  • To analyze the economic impact of wastage on pediatric vaccine formulary costs.
  • To determine maximum permissible wastage rates for vaccine inclusion in cost-effective formularies.

Main Methods:

  • Developed a vaccine selection algorithm integrating vaccine wastage data.
  • Compared lowest overall cost formularies with and without wastage costs.
  • Performed sensitivity analysis based on vaccine wastage rates.

Main Results:

  • Formularies incorporating wastage costs demonstrated different optimal vaccine selections.
  • Identified maximum permissible wastage rates for each vaccine to remain cost-effective.
  • Wastage significantly influences the economic viability of vaccine choices.

Conclusions:

  • Vaccine wastage is a critical factor in pediatric formulary cost optimization.
  • The developed algorithm provides valuable insights for healthcare organizations and providers.
  • Incorporating wastage data leads to more accurate and economically sound vaccine procurement decisions.

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