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[Correlation study between the connexin43 and the myocardial ischemia in rabbit]
Yang Chen1, Huazi Hu, Zhigang Liao
1West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China. chy5454@163.com
Fa Yi Xue Za Zhi
|May 21, 2004
Abstract
Objective:
To study the correlation between quantity of the connexin43 express and ischemia time in rabbit.
Methods:
Left coronary arteries were ligated to create early myocardial ischemia during distinct time, HBFP staining was used in the ischemia spot and SP method was used to show the expression of connexin43 and the ischemia are were measured by the computer image analysis.
Results:
Negative correlation was observed between the connexin43 quantity and the ischemia time. The significant was difference.
Conclusion:
With ischemia time raised, expression of connexin43 was descented.