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Published on: June 11, 2012
Insulin pump therapy for 1-6 year old children with type 1 diabetes
Naim Shehadeh1, Tadej Battelino, Avinoam Galatzer
1Pediatric Diabetes Unit, Meyer Children's Hospital of Haifa, Haifa, Israel. n_shehadeh@rambam.health.gov.il
Insights
Insulin pump therapy is safe and feasible for very young children with type 1 diabetes, significantly improving their quality of life and metabolic control. This treatment option offers benefits for managing pediatric diabetes.
Area of Science:
- Pediatric Endocrinology
- Diabetes Management
- Medical Technology
Background:
- Managing diabetes in preschool-aged children presents unique challenges for families and healthcare providers.
- Type 1 diabetes affects a growing number of young children, necessitating effective management strategies.
Purpose of the Study:
- To evaluate the feasibility and safety of insulin pump therapy in children aged 1-6 years.
- To assess the impact of insulin pump therapy on quality of life and glycemic control in this pediatric population.
Main Methods:
- A 12-month study involving 15 children (aged 1-6 years) with type 1 diabetes using insulin pump therapy.
- Collected data included insulin dosage, HbA1c levels, hypoglycemic events, and quality of life/treatment satisfaction scores.
- Compared outcomes with previous multiple daily injection (MDI) treatment.
Main Results:
- Significant reduction in HbA1c levels after 12 months of insulin pump therapy compared to baseline (P < 0.05).
- No significant differences observed in insulin dose or frequency of hypoglycemic events between pump and MDI therapy.
- Marked improvements in quality of life (DQOL) and treatment satisfaction (DTSQ) scores with insulin pump use (P < 0.001).
Conclusions:
- Insulin pump therapy is a feasible and safe treatment option for very young children with type 1 diabetes.
- This therapy demonstrably enhances the quality of life and glycemic control in this age group.
- Insulin pump therapy should be considered a viable therapeutic option for pediatric diabetes management.
Background:
The management of diabetes in preschool children poses unique difficulties for both the families and the medical team.
Objective:
To test the feasibility and safety of insulin pump therapy in the 1-6 year age group in order to improve quality of life and metabolic control.
Methods:
The study group comprised 15 type 1 diabetic children aged 1-6 years old (mean +/- SD, 3.8 +/- 1.2 years) from three diabetes centers. Insulin pump therapy was applied for 12 months. Data, including insulin dose, hemoglobin A1c, hypoglycemic events, as well as scores on the Diabetes Quality of Life Measure Questionnaire and the Diabetes Treatment Satisfaction Questionnaire, were collected and compared with the multiple daily injection treatment prior to entry into the study,
Results:
HbA1c was measured at the beginning of the study and at 2, 4, 8 and 12 months later; the respective levels (mean +/- SD) were 8.82 +/- 0.98, 8.45 +/- 1.05, 8.37 +/- 0.85, 8.32 +/- 0.71, 8.18 +/- 0.90%. HbA1c measurements after 12 months were significantly lower than at the beginning of the study (P < 0.05). There were no significant differences in insulin dose and the total number of hypoglycemic events. In both the DQOL and DTSQ scales there were significant differences in scores in favor of the insulin pump period (43.7 +/- 8.0 versus 33.7 +/- 7.9, P < 0.001; and 10.9 +/- 2.3 versus 14.5 +/- 2.3, P < 0.001), respectively.
Conclusions:
For very young diabetic children, insulin pump therapy improves quality of life and is feasible and safe. It should be considered as an optional mode of therapy for this age group.
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