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Updated: Aug 24, 2026

Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
A rare craniofacial cleft: numbers 7, 2, and 3 clefts accompanied by a single median lip pit
Michael Orlin Sigler1, John Stein, Ronald Zuker
1University of Sint Eustatius School of Medicine, Sint Eustatius, Netherlands-Antilles.
Objective:
A unique case of a unilateral partial Tessier no. 7 cleft accompanied by no. 2 and 3 clefts along with a single median lip pit is presented. The history, genetics, epidemiology, classifications, embryology, pathogenesis, and correction techniques are briefly reviewed. After an extensive review of the literature, we conclude that this particular constellation of anomalies has not previously been described.
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