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Very high pressure HPLC with 1 mm id columns
Luis A Colón1, José M Cintrón, Jason A Anspach
1Department of Chemistry, University at Buffalo, The State University of New York, NS Complex, Buffalo, New York 14260-3000, USA. lacolon@buffalo.edu
The Analyst
|May 21, 2004
Abstract:
Theoretical calculations and experimental data indicate that very high pressure HPLC can be performed using 1 and 1.5 mm id columns, and contrary to previous beliefs, the frictional heating generated does not appear to be detrimental to the separation.