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Updated: Aug 24, 2026

Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
[Regional anesthesia and analgesia applications in children and infants--II]
1Istanbul Universitesi Istanbul Tip Fakültesi, Algoloji Bilim Dali, Monoblok 34390, Istanbul, Turkey. ozyalcin@renetworks.net
Insights
Pediatric pain management has advanced with better understanding of pain pathways and pharmacology. Regional anesthetic techniques are now more accessible and beneficial for children, improving pain control.
Area of Science:
- Anesthesiology
- Pediatric Medicine
- Pain Management
Context:
- Traditional pediatric pain management lacked a clear rationale for analgesic use.
- Advances in understanding pain pathways and anesthetic pharmacology in children have emerged.
- Regional anesthesia techniques are increasingly accessible for pediatric patients.
Purpose:
- To review regional and topical anesthetic techniques for pediatric pain management.
- To highlight the growing interest and research in pediatric regional anesthesia.
- To discuss the advantages of regional anesthesia in infants and children.
Summary:
- Improved understanding of pediatric pain pathways and anesthetic pharmacology has led to formal analgesic regimens.
- Technological advancements and modified anatomical approaches have increased the accessibility of regional anesthetic techniques for children.
- Regional anesthesia offers significant benefits for pediatric pain management, similar to adults.
Impact:
- Enhanced understanding of pediatric pain mechanisms and anesthetic options.
- Improved clinical practice guidelines for pediatric pain control.
- Increased application of regional anesthesia in pediatric surgical and medical settings.
Abstract:
For years pediatric pain management has been practiced without clear rational use of analgesic therapy. The recent improved understanding of anatomical and physiological pathways of pain perceptions, and opioid and local anesthetic pharmacology in infants and children has led to the development of formal analgesic regimens for the management of pain. Also modifying the anatomical approach for children, studying new agents and combinations of agents, technological developments have made regional anesthetics techniques more accessible to children. For these reasons, in the last two decades, there has been an explosion of interest and research related to the use of regional anesthetic techniques in children. Regional anesthetic techniques have a significant but limited place in the practice of pain management in infants and children. However regional anesthetic techniques presumably afford many of the same advantages for the pediatric patients as it does in the adult patients. In this review, we discuss regional and topical anesthetic techniques available to clinicians who care for this population.
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