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Published on: July 18, 2014
Bridge-to-recovery from acute myocarditis in a 12-year-old child
Holger Hotz1, Joerg Linneweber, Pascal M Dohmen
1Klinik für kardiovaskuläre Chirurgie, Universitätsklinikum Charité der Humboldt-Universität zu Berlin, Schumannstrasse 21, 10119 Berlin, Germany.
Insights
Fulminant myocarditis can be fatal, particularly in children. This case study shows a rare pediatric success using the MEDOS HIA ventricular assist device for biventricular support, enabling full myocardial recovery.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Biomedical Engineering
Background:
- Fulminant myocarditis presents a significant risk of mortality and morbidity in pediatric patients.
- Mechanical circulatory support (MCS) is crucial for bridging pediatric patients with severe heart failure to recovery or transplantation.
- Successful weaning from biventricular support with complete myocardial recovery is exceptionally rare in children.
Observation:
- A 12-year-old girl diagnosed with fulminant myocarditis experienced intractable heart failure.
- The MEDOS HIA ventricular assist device was implemented in a biventricular bypass configuration.
- The device successfully off-loaded both ventricles, maintaining adequate cardiac output and end-organ function.
Findings:
- The patient received 19 days of continuous biventricular support.
- Anticoagulation was managed with intravenous heparin, and no neurological complications or pump thrombi were observed.
- Complete recovery of cardiac function was achieved, allowing for successful weaning from the device.
Implications:
- This case demonstrates the potential of the MEDOS HIA ventricular assist device for achieving myocardial recovery in pediatric patients with fulminant myocarditis.
- Successful biventricular support and weaning in a pediatric patient highlights advancements in MCS technology.
- The findings suggest that MCS can offer a viable alternative to transplantation, promoting long-term recovery in select pediatric cases.
Abstract:
Fulminant myocarditis causes substantial morbidity and mortality, especially in children and young adults. Mechanical circulatory support has become the standard therapy to bridge patients with intractable heart failure to either transplantation or myocardial recovery. Yet, successful weaning from biventricular support with full recovery is extremely rare in the pediatric population. This report describes the successful use of the MEDOS HIA ventricular assist device to bridge a 12-year-old girl to myocardial recovery in a biventricular bypass configuration. The left and right ventricle were completely off-loaded by the pumps and the device provided sufficient cardiac output to normalize end-organ function. Anticoagulation was maintained with i.v. heparin infusion. No neurological complications were detectable and the pump system was free of any macroscopic thrombi. After 19 days of support, cardiac function had recovered and the patient was successfully weaned from the device. Following physical rehabilitation, the patient was discharged home.
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