Bridge-to-recovery from acute myocarditis in a 12-year-old child

Holger Hotz1, Joerg Linneweber, Pascal M Dohmen

  • 1Klinik für kardiovaskuläre Chirurgie, Universitätsklinikum Charité der Humboldt-Universität zu Berlin, Schumannstrasse 21, 10119 Berlin, Germany.

Artificial Organs
|May 22, 2004
PubMed

Insights

Fulminant myocarditis can be fatal, particularly in children. This case study shows a rare pediatric success using the MEDOS HIA ventricular assist device for biventricular support, enabling full myocardial recovery.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Biomedical Engineering

Background:

  • Fulminant myocarditis presents a significant risk of mortality and morbidity in pediatric patients.
  • Mechanical circulatory support (MCS) is crucial for bridging pediatric patients with severe heart failure to recovery or transplantation.
  • Successful weaning from biventricular support with complete myocardial recovery is exceptionally rare in children.

Observation:

  • A 12-year-old girl diagnosed with fulminant myocarditis experienced intractable heart failure.
  • The MEDOS HIA ventricular assist device was implemented in a biventricular bypass configuration.
  • The device successfully off-loaded both ventricles, maintaining adequate cardiac output and end-organ function.

Findings:

  • The patient received 19 days of continuous biventricular support.
  • Anticoagulation was managed with intravenous heparin, and no neurological complications or pump thrombi were observed.
  • Complete recovery of cardiac function was achieved, allowing for successful weaning from the device.

Implications:

  • This case demonstrates the potential of the MEDOS HIA ventricular assist device for achieving myocardial recovery in pediatric patients with fulminant myocarditis.
  • Successful biventricular support and weaning in a pediatric patient highlights advancements in MCS technology.
  • The findings suggest that MCS can offer a viable alternative to transplantation, promoting long-term recovery in select pediatric cases.

Related Concept Videos

Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...