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A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Clinical review: new technologies for prevention of intravascular catheter-related infections
Stefania Cicalini1, Fabrizio Palmieri, Nicola Petrosillo
12nd Infectious Diseases Unit, Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, IRCCS, Rome, Italy. cicalini@inmi.it
Insights
Central venous catheters (CVCs) can cause bloodstream infections, but new technologies offer effective prevention. This review highlights advanced methods to reduce CVC-related infections in patients.
Area of Science:
- Infectious Diseases
- Medical Devices
- Patient Safety
Background:
- Intravascular catheters are crucial for patient care but pose infection risks, primarily catheter-related bloodstream infections (CRBSI).
- Central venous catheters (CVCs) present a higher CRBSI risk compared to peripheral catheters.
- CRBSI leads to increased morbidity, prolonged hospitalization, and elevated healthcare costs.
Purpose of the Study:
- To review novel technologies for preventing CVC-related bloodstream infections.
- To focus on advancements beyond traditional infection control measures.
Main Methods:
- Review of current literature on new technologies for CVC infection prevention.
- Description of strategies including antiseptic/antibiotic-impregnated catheters and dressings.
- Discussion of novel hub designs and antibiotic lock solutions.
Main Results:
- Several new technologies demonstrate effectiveness in reducing CRBSI risk.
- Impregnated catheters/dressings, new hub designs, and antibiotic lock solutions are promising preventive strategies.
Conclusions:
- Most CVC-related infections are preventable through advanced technological interventions.
- New technologies offer significant potential to decrease CRBSI incidence and associated complications.
Abstract:
Intravascular catheters have become essential devices for the management of critically and chronically ill patients. However, their use is often associated with serious infectious complications, mostly catheter-related bloodstream infection (CRBSI), resulting in significant morbidity, increased duration of hospitalization, and additional medical costs. The majority of CRBSIs are associated with central venous catheters (CVCs), and the relative risk for CRBSI is significantly greater with CVCs than with peripheral venous catheters. However, most CVC-related infections are preventable, and different measures have been implemented to reduce the risk for CRBSI, including maximal barrier precautions during catheter insertion, catheter site maintenance, and hub handling. The focus of the present review is on new technologies for preventing infections that are directed at CVCs. New preventive strategies that have been shown to be effective in reducing risk for CRBSI, including the use of catheters and dressings impregnated with antiseptics or antibiotics, the use of new hub models, and the use of antibiotic lock solutions, are briefly described.
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