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Temporomandibular joint dysfunction in Marfan syndrome
Oskar Bauss1, Reza Sadat-Khonsari, Christian Fenske
1Department of Orthodontics, Hannover Medical School, Germany. bauss.oskar@mh-hannover.de
Summary
Temporomandibular joint (TMJ) dysfunction is common in Marfan syndrome, affecting over half of patients. Early detection and management of TMJ issues are crucial for individuals with this genetic disorder.
Area of Science:
- Dentistry
- Genetics
- Radiology
Background:
- Marfan syndrome is a genetic disorder affecting connective tissue.
- Temporomandibular joint (TMJ) dysfunction symptoms can significantly impact quality of life.
Purpose of the Study:
- To determine the prevalence of temporomandibular joint (TMJ) dysfunction signs and symptoms in individuals with Marfan syndrome.
- To assess the clinical and imaging findings associated with TMJ dysfunction in this population.
Main Methods:
- A questionnaire was administered to 350 patients diagnosed with Marfan syndrome.
- Clinical examinations and magnetic resonance imaging (MRI) of the TMJ were performed on a subset of 21 patients.
Main Results:
- Over half of the patients (51.6%) reported symptoms of TMJ dysfunction.
- Subluxation symptoms were present in 24.2% of patients, and 34.9% were already receiving treatment for TMJ issues.
- Anterior disc displacement was found in 81.0% of examined patients, with 4 also showing osteoarthrosis.
Conclusions:
- Temporomandibular joint (TMJ) dysfunction is a significant and prevalent comorbidity in Marfan syndrome.
- These findings highlight the need for routine TMJ screening in Marfan syndrome patients.