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[A comparative description of amyloidosis in monkeys]
Abstract:
The paper contains the results of a postmortem study of 461 cases of amyloidosis in monkeys of 4 species (Papio hamadryas, Macaca mulatto, Macaca fascicularis and Macaca nemestrina) from the Sukhumi and Adler primatological facilities. Emergence of amyloidosis was found to be dependent on age; the frequency ratio at which separate organs are affected is presented; the specific disease signs are described for different monkey species. Generalized and isolated cases of amyloidosis are elucidated with the liver being the most vulnerable organ in macaques (64%) and the kidneys--in baboons (94%). A comparative description of different forms of amyloidosis in monkey and man was made use of to suggest using the amyloidosis in monkeys as a model process for studying the pathology in man.