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[New principles in the assessment of body functional status during sanatorium treatment]
Insights
Sanatorium treatment improved nonspecific adaptation of the organism (NSAO) in children. Higher initial adrenoreactivity correlated with better adaptation, suggesting personalized treatment approaches for children undergoing sanatorium care.
Area of Science:
- Pediatrics
- Physiology
- Health Sciences
Context:
- Study conducted on 151 children aged 6-14 years undergoing sanatorium treatment in Gelenzhik.
- Evaluated clinical status, nonspecific adaptation of the organism (NSAO), and erythrocyte beta-adrenoreactivity (b-ARE).
Purpose:
- To assess the effectiveness of sanatorium treatment by analyzing changes in NSAO and b-ARE.
- To determine the relationship between initial adrenoreactivity levels and treatment outcomes.
- To explore the utility of NSAO and b-ARE for personalized sanatorium treatment strategies.
Summary:
- Most children showed improved NSAO after sanatorium treatment, which also reduced b-ARE.
- Children with initially high adrenoreactivity exhibited a higher percentage of favorable NSAO.
- Subnormal adrenoreactivity was associated with significantly lower favorable NSAO rates.
- Children with high adrenoreactivity who experienced recent viral infections or tonsillitis had a higher incidence of unfavorable NSAO.
Impact:
- Findings suggest that evaluating b-ARE and NSAO is crucial for tailoring sanatorium treatment to individual children.
- This approach can optimize treatment efficacy and patient outcomes.
- Highlights the importance of physiological markers in guiding pediatric health interventions.
Abstract:
151 children aged 6-14 years received sanatorium treatment in Gelenzhik. The children were examined clinically before and after the treatment with estimation of nonspecific adaptation of the organism (NSAO) by L. Kh. Garkavi et al (1990) and adrenoreactivity by beta-adrenoreception of erythrocytes (b-ARE) using ARM-AGAT kits (Agat-Med., Moscow). The highest percent of favourable NSAO was seen in children with initially high adrenoreactivity. In children with subnormal adrenoreactivity it was 3-7 times less. Sanatorium treatment reduced b-ARE and improved NSAO in most of the children. In children with initially high adrenoreactivity (b-ARE 4-12 r.u.) who had had acute respiratory viral infection or tonsillitis, unfavourable NSAO number was higher. The trends in b-ARE and NSAO suggest the necessity of these indices evaluation for individual choice of sanatorium treatment and monitoring of its efficiency.
