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Obstructive sleep apnoea and stroke.
1Yale Center for Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
The Lancet. Neurology
|May 26, 2004
Summary
Obstructive sleep apnoea (OSA) is linked to stroke, potentially increasing stroke risk. Managing OSA may improve stroke recovery, but more research is needed to confirm causality.
Area of Science:
- Neurology
- Sleep Medicine
- Cardiovascular Science
Background:
- Stroke patients frequently have obstructive sleep apnoea (OSA), impacting recovery.
- Stroke can precipitate sleep-disordered breathing (SDB), but SDB may also be a stroke risk factor.
Purpose of the Study:
- To review the association between obstructive sleep apnoea (OSA) and stroke.
- To examine epidemiological and biological data on OSA and stroke causation and pathogenesis.
Main Methods:
- Literature review of epidemiological studies.
- Analysis of biological data exploring pathogenesis.
Main Results:
- Convincing evidence suggests OSA is a modifiable risk factor for stroke.
- The review synthesizes existing data on the OSA-stroke relationship.
Conclusions:
- OSA is strongly associated with stroke and may be a modifiable risk factor.
- Further prospective studies are required to definitively establish a cause-and-effect relationship between OSA and stroke.