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Rosmarinic acid from Zataria multiflora tops and in vitro cultures
A Mohagheghzadeh1, M Shams-Ardakani, A Ghannadi
1Department of Pharmacognosy, Shiraz Faculty of Pharmacy, Shiraz, Iran. mohaghegh@sums.ac.ir
Abstract:
Rosmarinic acid (RA) was obtained from Zataria multiflora tops' extract and its structure was confirmed by spectroscopic methods. Various in vitro cultures were established on Murashige and Skoog (MS) or Modified Tobacco (MT) medium containing growth hormones. The results indicated that cultures of Z. multiflora biosynthesize RA (55-355 mg/100 g dry wt.) and the highest accumulation were reached on MT media containing NAA 2 mg/l.
