[Analysis of malignancy change of oral leukoplakia]

235 cases of oral leukoplakia.which was confirmed histologically,had been observed and followed-up for 1-16 years.32 cases of them were malignancy changed,The incidence was 13.6%.The ratio in 18 male cases was 11.8% and 14.9% in female ones.The mean age of malignancy changing group was 53.4 years.The higher maligancy changing rate was shown in the granulation type and verrucous form type.The more often involved site was the tongue and the incidence was 75%,especially in the border and dorsal of the tongue.This study suggested that the pain display,local congestion,macule,the enlargement of the.esion proliferation,ulceration and firm of the mass were all the bodements of malignancy change.In this paper total 32 cases were followed-up 2 cases got recovery,the prognosis was good.