[Study on the biocompatibility of commonly used root canal filling materials]

The biocompatibility of commonly used four endodontic sealers and three brands of gutta-percha was studied by cell attachment experiment in vitro and SEM technique.The results indicated that all the materials tested had significant cytotoxicity.Clinically,in order to avoid irritrating periapical tissue mechanically and reduce cytotoxicity,overfilling should be avoided when possible.