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Updated: Aug 14, 2026

Murine Model of Intestinal Ischemia-reperfusion Injury
Published on: May 11, 2016
CT of small bowel ischemia
1Department of Radiology, Chi Mei Foundation Hospital, 901 Chung Hwa Road, Tainan 71010, Taiwan, Republic of China. cmh5200@mail.chimei.org.tw
Computed tomographic (CT) features can predict small bowel (SB) necrosis. Intramural gas in a thinned bowel wall or poor mucosal enhancement in a thickened SB wall indicates necrosis, with intramural gas signaling poor prognosis.
Area of Science:
- Radiology
- Gastroenterology
- Surgical Pathology
Background:
- Small bowel (SB) ischemia and necrosis are critical conditions requiring accurate diagnostic tools.
- Computed tomographic (CT) imaging is frequently used to evaluate abdominal pathologies.
- Correlating CT findings with clinical outcomes is essential for patient management.
Purpose of the Study:
- To evaluate CT features of small bowel (SB) ischemia and necrosis.
- To correlate these CT findings with patient prognosis and clinical outcomes.
- To identify specific CT signs indicative of bowel necrosis and poor prognosis.
Main Methods:
- Retrospective review of 68 surgically or angiographically proven cases of SB ischemia.
- Classification of CT features into three groups based on bowel wall thickness and associated findings.
- Evaluation of factors including bowel wall enhancement, SB dilatation, mesenteric edema, and vascular occlusion.
- Comparison of bowel necrosis rates and mortality using the chi-square test.
Main Results:
- Intramural gas and SB dilatation in thinned bowel walls (Group A) were associated with high necrosis rates (100% and 81%).
- Poor mucosal enhancement in thickened bowel walls (Groups B and C) indicated higher necrosis rates (86% and 100%).
- Intramural gas was the only CT finding significantly associated with higher mortality (75%).
Conclusions:
- Intramural gas in a thinned small bowel wall is a strong indicator of bowel necrosis.
- Poor mucosal enhancement in a thickened small bowel wall also suggests bowel necrosis.
- The presence of intramural gas on CT scans signifies a poor patient prognosis in cases of small bowel ischemia.
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