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Focal adhesion kinase (FAK) expression and phosphorylation in sea urchin embryos

María Guadalupe García1, Sarah Johnson Toney, Merrill B Hille

  • 1Department of Biology, University of Washington, Box 351800, Seattle, WA 98195-1800, USA.

Gene Expression Patterns : GEP
|May 27, 2004
PubMed

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Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
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