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Updated: Aug 24, 2026

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
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Published on: November 2, 2014

Novel therapies for recurrent ovarian cancer management

Snehal M Bhoola1, Ronald D Alvarez

  • 1University of Alabama at Birmingham, Division of Gynecologic Oncology, Birmingham, AL 35249, USA. sbhoola@uab.edu

Expert Review of Anticancer Therapy
|May 27, 2004
PubMed

Insights

Novel biologic therapies targeting ovarian cancer processes are under investigation. Ongoing clinical trials explore cytokines, monoclonal antibodies, and gene therapies, aiming to improve patient survival rates.

Area of Science:

  • Oncology
  • Pharmacology

Background:

  • Ovarian cancer pathogenesis involves complex cellular processes and molecules.
  • The development of targeted therapies is crucial for improving patient outcomes.

Purpose of the Study:

  • To review the progress of novel biologic agents in ovarian cancer treatment.
  • To summarize ongoing clinical studies evaluating these new therapeutic strategies.

Main Methods:

  • Review of current literature on biologic agents for ovarian cancer.
  • Analysis of ongoing Phase I/II and Phase III clinical trials.
  • Categorization of agents including cytokines, monoclonal antibodies, vaccines, protease inhibitors, and gene replacement systems.

Main Results:

  • Several biologic agents targeting ovarian carcinogenesis are in various trial phases.
  • Promising results from early-phase trials suggest potential efficacy.
  • Ongoing Phase III trials are critical for validating these novel therapies.

Conclusions:

  • Biologic agents represent a promising frontier in ovarian cancer treatment.
  • Further investigation and development may lead to combination therapies.
  • Improved survival for ovarian cancer patients is the ultimate goal.

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