Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Circadian rhythms and migraine.

G D Solomon1

  • 1Department of Internal Medicine, Cleveland Clinic Foundation, OH 44195.

Cleveland Clinic Journal of Medicine
|May 1, 1992
PubMed
Summary
This summary is machine-generated.

Migraine attacks exhibit a distinct circadian rhythm, not random occurrences. Most migraineurs experience headache onsets within a specific 4-hour window, peaking in the morning.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of primary headache: serendipity and science.

Cleveland Clinic journal of medicine·2001
Same author

Effect of guided imagery on quality of life for patients with chronic tension-type headache.

Headache·2001
Same author

Impact of migraine and migraine therapy on productivity and quality of life.

Neurology·2000
Same author

Impact of headache education program in the workplace.

Neurology·1999
Same author

Dosing of oral sumatriptan: a review of our first 104 patients.

Headache·1998
Same author

Quality of life in migraine.

Clinical neuroscience (New York, N.Y.)·1998

Area of Science:

  • Neurology
  • Chronobiology
  • Sleep Medicine

Background:

  • Migraine is a common neurological disorder.
  • The temporal pattern of migraine onset is not well understood.
  • Investigating circadian rhythms may reveal underlying mechanisms.

Purpose of the Study:

  • To determine if migraine onset follows a circadian pattern.
  • To analyze the timing of migraine attacks in a cohort of migraineurs.
  • To explore potential physiological mechanisms linked to migraine timing.

Main Methods:

  • Analysis of migraine onset times over 20 weeks in 15 individuals.
  • Statistical evaluation of attack frequency across different times of day.
  • Comparison of migraine onset patterns with known circadian rhythms of physiological markers.

Related Experiment Videos

Main Results:

  • 12 out of 15 migraineurs experienced 50% or more of their attacks within a 4-hour window.
  • A significant circadian variation in migraine onset was observed.
  • Peak migraine frequency occurred between 8 AM and 10 AM, with a notable increase from 6 AM to 8 AM and a decrease from 8 PM to 4 AM.

Conclusions:

  • Migraine onset exhibits a clear circadian rhythm.
  • The timing of migraine attacks parallels rhythms of myocardial infarction and hormonal fluctuations.
  • Alterations in vasomotor tone may play a role in initiating migraine attacks.