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PEG-supported synthesis of pyrazole oligoamides with peptide beta-sheet affinity

Katerina Cernovská1, Miriam Kemter, Hans-Christoph Gallmeier

  • 1Institut für Organische Chemie, Universität Regensburg, Germany.

Organic & Biomolecular Chemistry
|May 27, 2004
PubMed

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Peptide Bonds02:43

Peptide Bonds

A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...