Related Experiment Videos
Pitted enamel hypoplasia in tuberous sclerosis
J R Sampson1, D Attwood, A S al Mughery
1Institute of Medical Genetics, University Hospital for Wales, Cardiff, UK.
Clinical Genetics
|July 1, 1992
Abstract:
Thirty patients with tuberous sclerosis (from 29 different families) were examined for evidence of macroscopically visible pitted enamel hypoplasia. Of 23 patients with permanent teeth, 11 (48%) showed multiple enamel pits (mean 4.6 pits, range 3-9), but none were seen in six patients with deciduous teeth. Five of 563 controls (0.88%) had similar pitted enamel hypoplasia. Simple dental examination may be a useful adjunct in the assessment of patients with permanent teeth when a diagnosis of tuberous sclerosis is being considered, but is less likely to be helpful in the pre-school child.