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Dural sinus thrombosis after cardiopulmonary bypass

Mustafa Emir1, Kanat Ozisik, Kerim Cagli

  • 1Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey.

Perfusion
|May 28, 2004
PubMed

Insights

Pediatric dural sinus thrombosis is rare, especially after ventricular septal defect (VSD) repair. This case highlights Antiphospholipid Syndrome (APLS) and cardiopulmonary bypass (CPB) as key risk factors, warranting vigilance.

Area of Science:

  • Neurology
  • Pediatrics
  • Cardiology

Background:

  • Cerebral venous thrombosis is a known complication in conditions like congenital heart disease and hypercoagulable states.
  • Antiphospholipid Syndrome (APLS) is associated with an increased risk of thrombotic events.

Purpose of the Study:

  • To report a rare case of dural sinus thrombosis in a pediatric patient with APLS following ventricular septal defect (VSD) repair.
  • To identify potential risk factors and emphasize the need for screening in similar cases.

Main Methods:

  • Case report of a pediatric patient who underwent VSD repair.
  • Cranial computed tomography (CT) scan to diagnose dural sinus thrombosis and cerebral edema.
  • Review of patient's medical history for risk factors including APLS and cardiopulmonary bypass (CPB).

Main Results:

  • The patient developed a stroke post-VSD repair.
  • Cranial CT revealed dural sinus thrombosis and severe cerebral edema.
  • APLS and CPB were identified as significant risk factors for thrombosis.

Conclusions:

  • This is the first reported case of dural sinus thrombosis in a pediatric patient with APLS after VSD repair.
  • Screening for dural sinus thrombosis should be considered in APLS patients undergoing CPB, particularly after cardiac surgery.
  • Increased awareness and vigilance are crucial for managing thrombotic risks in this vulnerable pediatric population.

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