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Limited Wegener's granulomatosis presenting with complete heart block
N O Ghaussy1, T W Du Clos, P A Ashley
1Division of Rheumatology, Department of Internal Medicine, University of New Mexico Health Sciences Center, Veterans Administration Hospital, Albuquerque, NM 87131, USA. NGhaussy@salud.unm.edu
Abstract:
Complete heart block associated with Wegener's granulomatosis (WG) is rare, and has not previously been reported with 'limited' WG. The case of a 36-year-old man who presented with complete heart block due to 'limited' WG [positive cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA) on indirect immunofluorescence, positive serum antibodies to proteinase-3, and inflammatory sinus disease seen on computerized tomography (CT) without renal or pulmonary involvement] is presented. In addition, a gallium-scan fused with a myocardial perfusion scan and cardiac magnetic resonance imaging (MRI) suggested focal inflammation near the atrioventricular (AV) node.