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Related Experiment Videos

Performing bone marrow biopsies with or without sedation: a comparison.

I Giannoutsos1, H Grech, T Maboreke

  • 1Department of Haematology, Royal Berkshire Hospital, Reading, UK. igiannoutsos@reading49.freeserve.co.uk

Clinical and Laboratory Haematology
|May 28, 2004
PubMed
Summary

Most patients undergoing bone marrow aspirate and trephine (BMAT) prefer local anesthetic (LA) only. Intravenous sedation (ISED) with LA reduced pain and apprehension, especially for repeat procedures.

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Area of Science:

  • Medical procedures
  • Patient experience
  • Anesthesiology

Background:

  • Intravenous sedation (ISED) is often used with local anesthetic (LA) for bone marrow aspirate and trephine (BMAT).
  • The optimal use and benefits of ISED for BMAT are not well-defined.

Purpose of the Study:

  • To evaluate patient preference and outcomes for BMAT performed with LA only versus LA with ISED.
  • To identify factors influencing the choice and effectiveness of sedation during BMAT.

Main Methods:

  • A questionnaire was administered to 112 patients post-BMAT.
  • Data collected included patient-reported pain scores, apprehension levels, procedure duration, biopsy core length, and complications.
  • Patient decisions regarding sedation were recorded.

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Main Results:

  • 68% of patients opted for LA only and were largely satisfied.
  • Patients receiving ISED reported lower pain scores (1 vs. 3) and less apprehension about repeat procedures.
  • Patients undergoing repeat BMAT showed a slight preference for ISED.

Conclusions:

  • While ISED can reduce pain and apprehension during BMAT, most patients are satisfied with LA alone.
  • Patients should have the option of ISED if resources permit.
  • Current sedation practices for BMAT warrant a large-scale audit to ensure adherence to guidelines.