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GEHA--the pan-European "Genetics of Healthy Aging" project

Almut Nebel1, Stefan Schreiber

  • 1Institute for Clinical Molecular Biology, University Hospital of the Christian Albrechts-University, 24105 Kiel, Germany.

Science of Aging Knowledge Environment : SAGE KE
|May 28, 2004
PubMed

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...