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Related Experiment Videos

Intrapericardial carcinoid metastasis.

Nicholas Collins1, Greg Bellamy, Peter Hayes

  • 1Cardiovascular Unit, John Hunter Hospital, Newcastle, NSW, Austalia.

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
|May 28, 2004
PubMed
Summary
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Metastasis from carcinoid tumors, typically to the liver, can cause carcinoid syndrome. This case highlights an unusual pericardial metastasis without valvular disease, expanding understanding of cardiac complications.

Area of Science:

  • Oncology
  • Cardiology
  • Pathology

Background:

  • Carcinoid tumors are neuroendocrine malignancies.
  • Metastasis commonly affects the liver, leading to carcinoid syndrome with secretory symptoms and right-sided valvular heart disease.

Observation:

  • A 50-year-old patient with confirmed carcinoid syndrome presented with a large mass detected posterior to the interatrial septum via echocardiography.
  • Advanced imaging (transesophageal echocardiography, MRI) confirmed the mass was within the pericardial space, without myocardial involvement.

Findings:

  • Surgical removal (thoracotomy) and subsequent histology confirmed the mass to be metastatic carcinoid disease.
  • This represents a previously unidentified site of cardiac metastasis from carcinoid tumors.

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Implications:

  • While cardiac valvular complications are known risks in carcinoid syndrome, this case reveals pericardial metastasis as a rare presentation.
  • Highlights the importance of comprehensive cardiac screening in patients with carcinoid syndrome, considering diverse metastatic patterns.