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Karla V Ballman1, Diane E Grill, Ann L Oberg

  • 1Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. ballman@mayo.edu

Bioinformatics (Oxford, England)
|May 29, 2004
PubMed
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RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...