Related Experiment Videos
Inhibition by basic drugs of digoxin secretion into human bile
1Department of Clinical Pharmacology, Karolinska Institute, Huddinge University Hospital, Sweden.
European Journal of Clinical Pharmacology
|January 1, 1992
Abstract:
Bile samples from previous interaction studies in man were re-analysed by a combined HPLC/radioimmunoassay method. Quinidine, quinine and verapamil but not probenecid or spironolactone were found to inhibit the biliary secretion of unchanged digoxin.