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Related Experiment Videos

Rare nocturnal headaches.

Anna S Cohen1, Holger Kaube

  • 1Department of Clinical Neurology, Institute of Neurology, London, UK.

Current Opinion in Neurology
|May 29, 2004
PubMed
Summary
This summary is machine-generated.

Rare nocturnal headaches, including cluster headaches and hypnic headaches, are linked to sleep patterns. Emerging evidence suggests these are chronobiological disorders, responding to treatments affecting the sleep-wake cycle.

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Area of Science:

  • Neurology
  • Sleep Medicine
  • Chronobiology

Background:

  • Headaches occurring during sleep are uncommon but debilitating.
  • Specific syndromes include cluster headaches, hypnic headache, and exploding head syndrome.

Purpose of the Study:

  • To review rare nocturnal headache disorders.
  • To focus on cluster headaches and hypnic headaches in relation to sleep.

Main Methods:

  • Review of existing literature and polysomnographic studies.
  • Analysis of functional imaging findings related to hypothalamic activation.
  • Examination of treatment responses to melatonin and lithium.

Main Results:

  • Cluster headaches and hypnic headaches correlate with rapid eye movement sleep.

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  • Hypothalamic activation is observed, suggesting a role in circadian rhythms.
  • These headache types show positive responses to melatonin and lithium therapy.

    • Conclusions:

    • Cluster headache and hypnic headache are increasingly recognized as chronobiological disorders.
    • Disruptions in the sleep-wake cycle are implicated in the pathophysiology of these headaches.