Related Experiment Video
Updated: Aug 24, 2026
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Surgical correction of craniosynostosis in malignant osteopetrosis
Michael Krimmel1, Gerhard Niemann, Bernd Will
1Departments of Oral and Maxillofacial Plastic Surgery, University Hospital Tübingen, Germany. Michael.Krimmel@med.uni-tuebingen.de
Abstract:
In osteopetrosis, bone healing is complicated by progressive sclerosis. A 2-year-old blind boy with malignant osteopetrosis developed increased intracranial pressure secondary to craniosynostosis. Osteopetrosis had already been treated with bone marrow transplantation (BMT), and bone remodeling seemed to be restored. A craniotomy was performed. The postoperative course and bone healing were uneventful. After successful BMT, craniofacial procedures seem to be possible without a high risk for osteomyelitis.
