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Updated: Aug 24, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[Closed subfascial v.a.C.-therapy in periprosthetic hip infections]
J Kelm1, K Anagnostakos, E Schmitt
1Orthopädische Universitätsklinik Homburg/Saar. jk66421@hotmail.com
Abstract:
Infections after hip arthroplasty can lead to protracted and complicated treatments. A great problem is thereby the persistant secretion after surgical revision. 8 patients (3 x after acetabulum cup replacement, 2 x after Girdlestone hip, 2 x after spacer implantation and one case of rearthroplasty) have been treated with a V.A.C.-therapy after bacterial infection and persistant wound secretion. In all cases a pathogen organism could be identified during the frustrated attempts of sanitation. After meticulous debridement and jet lavage in each case, 1-3 polyvinyl sponges have been placed either periprosthetic or in the resection cavity with a transcutan tube outgoing. The wounds have been closed in layers. Initially a pressure of 200 mm Hg via V.A.C. has been attached. After 48-72 h an alteration from haemorrhagic to serous secret could be observed and afterwards the pressure has been reduced to 150 mm Hg. After a mean period of 11 days (8-13) the infection parameters have been retrogressive, the wound secretion was obviously reduced and the sponges were removed. During the remaining hospitalization of each patient no complications occured. In the mean follow-up of 21 months (2-46) no reinfections have been observed. Although the V.A.C.-therapy does not count to the primary therapy concepts of periprosthetic hip infections, it stands for an effective therapy option in exclusive cases.
Insights
Vacuum-assisted closure (V.A.C.) therapy effectively managed persistent wound secretion in eight patients following hip arthroplasty infections. This approach, used after surgical revision, showed positive outcomes and no reinfections during follow-up.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Wound Management
Context:
- Periprosthetic hip infections often result in complex, prolonged treatments.
- Persistent wound secretion post-revision surgery presents a significant clinical challenge.
Purpose:
- To evaluate the efficacy of Vacuum-assisted closure (V.A.C.) therapy in managing persistent wound secretion after hip arthroplasty infections.
- To assess the outcomes and complication rates associated with V.A.C. therapy in this patient cohort.
Summary:
- Eight patients with persistent wound secretion after hip arthroplasty revision due to bacterial infection were treated with V.A.C. therapy.
- Following debridement and lavage, polyvinyl sponges were placed, and V.A.C. therapy was initiated, with pressure adjustments based on secretion type.
- Treatment resulted in reduced infection parameters and wound secretion within a mean of 11 days, with no reinfections observed during a mean follow-up of 21 months.
Impact:
- V.A.C. therapy offers a viable, effective treatment option for refractory periprosthetic hip infections with persistent secretion.
- This study highlights the potential of negative pressure wound therapy in complex orthopedic surgical site infections.
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