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Xanthogranulomatous cholecystitis

Sushil Budhiraja1, J D Wig, N M Gupta

  • 1Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh 160012.

Journal of the Indian Medical Association
|June 1, 2004
PubMed

Insights

Xanthogranulomatous cholecystitis presents similarly to chronic cholecystitis and is associated with gallstones. Surgical removal (cholecystectomy) is curative, with no malignancy found in these cases.

Area of Science:

  • Gastroenterology
  • Pathology
  • Surgical Oncology

Background:

  • Xanthogranulomatous cholecystitis (XGC) is a rare, benign gallbladder disease.
  • It can mimic malignant conditions clinically and radiologically.
  • Associated gallstones are a common finding.

Purpose of the Study:

  • To report clinical characteristics and outcomes of xanthogranulomatous cholecystitis.
  • To differentiate XGC from gallbladder cancer.
  • To evaluate the efficacy of cholecystectomy for XGC.

Main Methods:

  • Retrospective review of twelve cases of XGC.
  • Clinical presentation analysis.
  • Histopathological examination of resected gallbladders.

Main Results:

  • Clinical presentation resembled chronic cholecystitis.
  • All patients had concurrent gallstones.
  • Histopathology confirmed XGC, with no evidence of malignancy.
  • Cholecystectomy provided a complete cure.

Conclusions:

  • Xanthogranulomatous cholecystitis is a distinct entity from gallbladder cancer.
  • Diagnosis relies on histopathological examination.
  • Cholecystectomy is a definitive and curative treatment for XGC.

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