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Prokinetic agents.

J C Reynolds1, P E Putnam

  • 1Division of Gastroenterology and Hepatology, University of Pittsburgh School of Medicine, Pennsylvania.

Gastroenterology Clinics of North America
|September 1, 1992
PubMed
Summary
This summary is machine-generated.

Prokinetic agents enhance gastrointestinal motility. This review covers their action mechanisms and use in treating motility disorders like reflux, gastroparesis, and constipation.

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Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Prokinetic agents are crucial for managing gastrointestinal (GI) motility disorders.
  • Understanding their mechanisms is key to effective treatment.

Purpose of the Study:

  • To review the current understanding of prokinetic agent mechanisms.
  • To assess their clinical utility in various GI motility disorders.

Main Methods:

  • Literature review of prokinetic agents.
  • Analysis of mechanisms of action.
  • Evaluation of clinical applications.

Main Results:

  • Prokinetic agents stimulate GI motility through various pathways.
  • Effective in treating gastroesophageal reflux, gastroparesis, and constipation.

Conclusions:

  • Prokinetic agents remain vital for GI motility disorders.
  • Further research can optimize their therapeutic use.