Related Experiment Videos
Lung involvement in systemic sclerosis sine scleroderma treated by plasma exchange
C Ferri1, L Bernini, G Gremignai
1Rheumatology Unit, University of Pisa, Italy.
The International Journal of Artificial Organs
|July 1, 1992
Summary
Systemic sclerosis sine scleroderma can manifest as lung disease. This report details two new cases, including a woman, and the impact of plasma exchange therapy on pulmonary interstitial fibrosis.
Area of Science:
- Rheumatology
- Pulmonology
- Internal Medicine
Background:
- Systemic sclerosis sine scleroderma (SScScl) is a rare variant of systemic sclerosis.
- It characteristically presents without skin thickening but can involve internal organs, notably the lungs.
- Pulmonary interstitial fibrosis is a known, albeit uncommon, manifestation of SScScl.
Observation:
- This study presents two new cases of SScScl with significant lung involvement.
- One of the reported cases is female, expanding the previously documented male-only cohort.
- The clinical and serological characteristics of these patients were meticulously documented.
Findings:
- The cases highlight the potential for SScScl to present primarily as pulmonary interstitial fibrosis.
- The inclusion of a female patient broadens the known demographic profile of this specific SScScl presentation.
- Therapeutic plasma exchange was administered, and its effects on the lung condition were observed.
Implications:
- Early recognition of SScScl presenting as lung disease is crucial for timely diagnosis and management.
- Understanding the diverse presentations of SScScl aids in developing targeted therapeutic strategies.
- Further research into the efficacy of treatments like plasma exchange for SScScl-related lung disease is warranted.