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Related Experiment Videos

Snuffles in infants--infection or autonomic dysfunction.

T G Teoh1, G P Fox, T G Matthews

  • 1Rotunda Hospital, Dublin.

Irish Journal of Medical Science
|February 1, 1992
PubMed
Summary

Infant snuffles, or noisy nasal breathing, may be linked to impaired autonomic nervous system function rather than infection. This study found a higher incidence of postural hypotension in infants with snuffles, suggesting a potential role for vasomotor control issues.

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Area of Science:

  • Pediatrics
  • Neonatology
  • Autonomic Nervous System Function

Background:

  • Infant snuffles (noisy nasal breathing with mucus) are common in the first three months of life.
  • Traditionally attributed to upper respiratory tract infections, this is often unproven in infants without other infection signs.

Purpose of the Study:

  • To investigate the potential role of impaired vasomotor control (autonomic function) in the development of infant snuffles.
  • To assess if changes in body position affect blood pressure in infants with snuffles.

Main Methods:

  • Compared resting blood pressure changes upon postural change (supine to upright) in 50 infants with snuffles and 50 healthy controls.
  • Defined postural hypotension as a fall of greater than 10% in resting blood pressure.
  • All infants were healthy, without signs of acute infection or medication.

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Main Results:

  • Postural hypotension was observed in 22 out of 50 infants with snuffles.
  • Only 4 out of 50 healthy control infants exhibited postural hypotension.
  • This difference was statistically significant (Chi square 16.84, p < 0.001).

Conclusions:

  • The findings suggest a potential association between infant snuffles and impaired vasomotor control.
  • Autonomic dysfunction may play a role in the pathogenesis of snuffles in some infants.