[A case of large-cell lung cancer with marked leukocytosis successfully treated with chemoradiotherapy]

A 45-year-old woman was transferred to our hospital for further examination of a persistent fever, marked leukocytosis and abnormal shadow on chest CT scan. At the time of admission, her leukocyte count was 48,800/microliter and her chest CT scan showed a solitary nodule in the right upper lobe with hilar and mediastinal lymphadenopathy. A US-guided biopsy revealed a large-cell carcinoma. She was given radiation (total 60 Gy) and 4 courses of chemotherapy with paclitaxel (150 mg/m2) in combination with carboplatin (AUC = 5). The primary tumor and swollen lymph nodes disappeared and leukocyte count normalized. Although 3 years have passed, no recurrence has been observed.