Endometrial involvement by intra-abdominal diffuse malignant mesothelioma

A 49-year-old patient presented with an adnexal mass. Endometrial curettage showed a proliferative phase and suspicious fragment resembling Arias Stella reaction. Laparotomy revealed an extensive nodular intra-abdominal tumor involving the bilateral ovaries. Microscopic findings were similar to the suspicious endometrial fragment in the curettage specimen. Histochemical and immunohistochemical studies confirmed the diagnosis of diffuse malignant mesothelioma with metastasis to the endometrium. This is the first reported case to our knowledge in the English literature.