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[Brachyury in German Holstein cattle].

C Bähr¹, O Distl

¹Institut für Tierzucht und Vererbungsforschung der Tierärztlichen Hochschule Hannover.

DTW. Deutsche Tierarztliche Wochenschrift

|June 3, 2004

Summary

Short tails in German Holstein cattle suggest a genetic link. This inherited congenital anomaly, likely autosomal recessive, affects cattle from various farms, indicating brachyury as a potential cause.

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Area of Science:

Veterinary Genetics
Animal Breeding
Congenital Anomalies

Background:

Short tail phenotype observed in German Holstein cattle.
Affected animals exhibited no other congenital anomalies.
Parental generation showed no tail abnormalities.

Purpose of the Study:

Investigate the inheritance pattern of the short tail anomaly in German Holstein cattle.
Determine if the condition is environmentally induced or genetic.
Identify potential genetic mechanisms, such as brachyury.

Main Methods:

Clinical examination of affected cattle.
Pedigree analysis to trace lineage and relationships.
Calculation of coefficients of relationship between affected animals.

Main Results:

Eleven German Holstein cattle presented with short tails.
Affected animals originated from different farms but were related.
Pedigree data suggested monogenic or oligogenic autosomal recessive inheritance.
No obvious environmental factors were identified.

Conclusions:

The short tail condition in German Holstein cattle is likely an inherited congenital anomaly.
Brachyury is a probable cause, consistent with autosomal recessive inheritance.
Further genetic investigation is warranted to confirm the causative gene and mutation.

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