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[Study on distribution of safflor yellow A in tissues of mice]
Yue-qing Liu1, Hai-tao Zhou, Kai-shun Bi
1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Aim:
To study the distributive character of safflor yellow A in mice.
Methods:
A RP-HPLC method for the determination of safflor yellow A in tissues was established and applied to determine safflor yellow A in biological samples.
Results:
After iv injection of Safflor yellow A in mice, the AUC of safflor yellow A was hightest in plasma, followed by kidney, liver, lung, heart, spleen. But it was not found in the brain.
Conclusion:
The distribution of safflor yellow A in the body is abroad and the speed of its process is swift.
