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Metastatic microcystic adnexal carcinoma: an autopsy case
Masayoshi Ohta1, Michiaki Hiramoto, Hisashi Ohtsuka
1Department of Plastic and Reconstructive Surgery, Kyoto University Hospital, Kyoto, Japan. emp-ota@kuhp.kyoto-u.ac.jp
Background:
Microcystic adnexal carcinoma is a clinically aggressive, local destructive sweat gland carcinoma with a high rate of recurrence, but regional or distant metastasis is quite rare.
Objective:
The objective was to describe an autopsy case of microcystic adnexal carcinoma with hematogenous metastasis and perineural intracranial spreads.
Methods:
This is an autopsy case of a 73-year-old woman with hematogenous metastasis of microcystic adnexal carcinoma followed for more than 20 years.
Result:
The autopsy study revealed that the metastatic lesions were located in the perineural intracranial spread, left clavicle bone, bilateral 12th ribs, and liver.
Conclusion:
Physicians should be aware that microcystic adnexal carcinoma is capable of metastasis to the liver and bones with intracranial spread along the optic nerve into the cranium.
