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Urgent off-pump coronary artery bypass grafting in a patient with HIV
Mitsuhiro Kawata1, Kazuhiko Higuchi, Kenji Koseni
1Department of Cardiac Surgery, Asahi General Hospital, Asahi City, Chiba, Japan. mkawata-ths@umin.ac.jp
Insights
Urgent off-pump coronary artery bypass grafting (CABG) is safe for patients with human immunodeficiency virus (HIV). This procedure did not negatively impact CD4+ cell counts or HIV viral load in a recent case study.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Innovation
Background:
- Coronary artery disease (CAD) is a significant concern in patients with human immunodeficiency virus (HIV).
- Off-pump coronary artery bypass grafting (CABG) offers a potential alternative to traditional CABG, especially in high-risk populations.
- The safety and impact of off-pump CABG on HIV disease progression require careful evaluation.
Observation:
- A 54-year-old patient with unstable angina pectoris and HIV infection underwent urgent off-pump CABG.
- Perioperative monitoring included CD4+ cell counts and HIV-RNA viral load.
- The patient experienced a successful surgical outcome.
Findings:
- Off-pump CABG did not lead to a decrease in CD4+ cell count.
- The procedure did not adversely affect the patient's HIV infection status.
- Surgical recovery was uneventful, with stable immunological markers.
Implications:
- Off-pump CABG can be considered a viable and safe surgical option for HIV-infected patients with severe coronary artery disease.
- This approach may help preserve immune function in HIV patients undergoing cardiac surgery.
- Further research is warranted to confirm these findings in larger cohorts and explore long-term outcomes.
Abstract:
We report a case of successful urgent off-pump coronary artery bypass grafting (CABG) for unstable angina pectoris in a 54-year-old human with human immunodeficiency virus (HIV) infection. We studied the changes in CD4+ cells and HIV-RNA copy during the perioperative period. The results showed that off-pump CABG did not reduce the CD4+ cell count and did not affect the condition of HIV infection in this patient.
